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T cell-mediated oral tolerance is intact in germ-free mice

โœ Scribed by K. L. W. Walton; J. A. Galanko; R. Balfour Sartor; N. C. Fisher


Book ID
108699311
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
246 KB
Volume
143
Category
Article
ISSN
0009-9104

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The liver appears to play an important role in immunological tolerance, for example, during allo-transplantation. We investigated tolerance mechanisms in the model of concanavalin A (ConA)-induced immune-mediated liver injury in mice. We found that a single injection of a sublethal ConA dose to C57B