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T cell dynamics before and after HIV antiviral therapiy

✍ Scribed by G Gorochov

Book ID
117576266
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
115 KB
Volume
52
Category
Article
ISSN
0753-3322

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We analyse mathematical models comparing the in vivo dynamics of macrophage-and T cell infection by HIV. Experiments suggest that HIV can only replicate in activated T cells whereas cell activation may not be required for successful replication in macrophages. These assumptions lead to fundamentally