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Modeling the dynamics of HIV and T cells during primary infection

โœ Scribed by Prashant Kr. Srivastava; Peeyush Chandra


Book ID
108226103
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
604 KB
Volume
11
Category
Article
ISSN
1468-1218

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Dynamics of Macrophage and T Cell Infect
โœ Dominik Wodarz; Alun L. Lloyd; Vincent A.A. Jansen; Martin A. Nowak ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 176 KB

We analyse mathematical models comparing the in vivo dynamics of macrophage-and T cell infection by HIV. Experiments suggest that HIV can only replicate in activated T cells whereas cell activation may not be required for successful replication in macrophages. These assumptions lead to fundamentally