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T-cell dynamics before and after HIV antiviral therapy

✍ Scribed by G. Gorochov

Book ID
117575208
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
117 KB
Volume
53
Category
Article
ISSN
0753-3322

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We analyse mathematical models comparing the in vivo dynamics of macrophage-and T cell infection by HIV. Experiments suggest that HIV can only replicate in activated T cells whereas cell activation may not be required for successful replication in macrophages. These assumptions lead to fundamentally