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T cell activation by anti-idiotypic antibody: mechanism of interaction with antigen-reactive T cells

✍ Scribed by Ann D. M. Rees; Anne Scoging; Nicola Dobson; Kriangsak Praputpittaya; Douglas Young; Juraij Ivanyi; Jonathan R. Lamb

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
551 KB
Volume
17
Category
Article
ISSN
0014-2980

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Induction of T and B cell immunity by an
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## Abstract A small dose of the IgG~1~ fraction of anti‐idiotypic antibody (āId 1) raised in guinea pigs against a strain A/J antibody specific for streptococcal Group A carbohydrate sensitizes A/J mice against Group A streptococci. This is opposed to the previously established suppressive function