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t-Butyl Ester of 7-Aminocephalosporanic Acid

โœ Scribed by Stedman, R. John


Book ID
127038033
Publisher
American Chemical Society
Year
1966
Tongue
English
Weight
118 KB
Volume
9
Category
Article
ISSN
0022-2623

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On the stereochemical purity of (+)-7-am
โœ Thomas Oberhauser; Vladimir Meduna ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 740 KB

+)-7-Aminocephalosporanic acid (18a) and (+)-7-epi-aminocephalosporanic acid (4a) have been synthesized. A chiral HPLC method has been developed for the separation of the four stereoisomers. Natural (+)-7-aminocephalosporanic acid (1) was demonstrated to be enantiomerically (ee >> 99.95%) and diaste