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Systemic administration of doxorubicin-containing liposomes in cancer patients: a phase I study

✍ Scribed by A. Gabizon; T. Peretz; A. Sulkes; S. Amselem; R. Ben-Yosef; N. Ben-Baruch; R. Catane; S. Biran; Y. Barenholz


Book ID
118154808
Publisher
Elsevier Science
Year
1989
Weight
926 KB
Volume
25
Category
Article
ISSN
0277-5379

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## Abstract ## BACKGROUND Pegylated liposomal doxorubicin (PEG‐LD) and gemcitabine have single‐agent activity in breast and ovarian carcinoma patients. We conducted a Phase I trial to evaluate the maximum tolerated dose (MTD) and toxicities of this combination in patients with advanced malignancie