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A Phase I Study of Pegylated Liposomal Doxorubicin and Irinotecan in Patients with Solid Tumors

✍ Scribed by Morgensztern, Daniel; Baggstrom, Maria Q.; Pillot, Giancarlo; Tan, Benjamin; Fracasso, Paula; Suresh, Rama; Wildi, Jonathan; Govindan, Ramaswamy


Book ID
120558434
Publisher
S. Karger AG
Year
2009
Tongue
English
Weight
133 KB
Volume
55
Category
Article
ISSN
0009-3157

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Phase I study of pegylated liposomal dox
✍ Paula M. Fracasso; Kristie A. Blum; Benjamin R. Tan; Carole L. Fears; Nancy L. B πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 71 KB πŸ‘ 2 views

## Abstract ## BACKGROUND Pegylated liposomal doxorubicin (PEG‐LD) and gemcitabine have single‐agent activity in breast and ovarian carcinoma patients. We conducted a Phase I trial to evaluate the maximum tolerated dose (MTD) and toxicities of this combination in patients with advanced malignancie