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Synthetic vaccines: I. Synthesis of multivalent Tn antigen cluster-lysyllysine conjugates

✍ Scribed by Tatsushi Toyokuni; Barbara Dean; Sen-itiroh Hakomori

Book ID: 104226690
Publisher: Elsevier Science
Year: 1990
Tongue: French
Weight: 293 KB
Volume: 31
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)94669-0

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on the occasion of his 60th birthday A common feature of oncogenic transformed cells is the overexpression of oligosaccharides, such as Globo-H, Lewis Y , and Tn antigens. [1][2][3][4] Numerous studies have shown that this abnormal glycosylation can promote metastasis, [5] and hence its expression i