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Chemoselective Assembly and Immunological Evaluation of Multiepitopic Glycoconjugates Bearing Clustered Tn Antigen as Synthetic Anticancer Vaccines

✍ Scribed by Grigalevicius, Saulius; Chierici, Sabine; Renaudet, Olivier; Lo-Man, Richard; Dériaud, Edith; Leclerc, Claude; Dumy, Pascal

Book ID
127365921
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
258 KB
Volume
16
Category
Article
ISSN
1043-1802

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Dedicated to Professor Steven V. Ley on the occasion of his 60th birthday A common feature of oncogenic transformed cells is the overexpression of oligosaccharides, such as Globo-H, Lewis Y , and Tn antigens. [1][2][3][4] Numerous studies have shown that this abnormal glycosylation can promote metas