ChemInform Abstract: Synthesis of Tn and Sialyl Tn Antigen—Lipid A Analogue Conjugates for Synthetic Vaccines.
✍ Scribed by K. MIYAJIMA; T. NEKADO; K. IKEDA; K. ACHIWA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 27 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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Dedicated to Professor Steven V. Ley on the occasion of his 60th birthday A common feature of oncogenic transformed cells is the overexpression of oligosaccharides, such as Globo-H, Lewis Y , and Tn antigens. [1][2][3][4] Numerous studies have shown that this abnormal glycosylation can promote metas
on the occasion of his 60th birthday A common feature of oncogenic transformed cells is the overexpression of oligosaccharides, such as Globo-H, Lewis Y , and Tn antigens. [1][2][3][4] Numerous studies have shown that this abnormal glycosylation can promote metastasis, [5] and hence its expression i