A stereocontrolled and practical synthetic route to the acetal 2a, a degradation product of palytoxin, in optically active form is described. Palytoxin, the toxic principle isolated from marine soft corals of the genus Palythoa, is the most poisonous substance known to date, except for a few polype
✦ LIBER ✦
Synthetic studies on palytoxin stereocontrolled practical synthesis of the C.23 – C.37 segment
✍ Scribed by J. Leder; H. Fujioka; Y. Kishi
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 247 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
An 8-step synthesis of the bicyclic ketal 2 from l-(+)-citronella1 is described. -
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