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Synthetic Studies on (+)-Manzamine A: Stereoselective Synthesis of the Tetracyclic Core Framework

✍ Scribed by Kita, Yoichi; Toma, Tatsuya; Kan, Toshiyuki; Fukuyama, Tohru

Book ID: 121492360
Publisher: American Chemical Society
Year: 2008
Tongue: English
Weight: 121 KB
Volume: 10
Category: Article
ISSN: 1523-7060
DOI: 10.1021/ol801111r

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Synthetic Studies on Manzamine A: Construction of the Tetracyclic ABCE Ring Substructure. -A completely different route to the tetracyclic ABCE ring substructure (V) of manzamine A is described. Beginning with an advanced intermediate (I) the procedure is characterized by the formation of the A rin