ChemInform Abstract: Synthetic Studies on Manzamine A: Construction of the Tetracyclic ABCE Ring Substructure.
β Scribed by S. LI; S. YAMAMURA; H. HOSOMI; S. OHBA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Synthetic Studies on Manzamine A: Construction of the Tetracyclic ABCE Ring Substructure.
-A completely different route to the tetracyclic ABCE ring substructure (V) of manzamine A is described. Beginning with an advanced intermediate (I) the procedure is characterized by the formation of the A ring in the final step.
π SIMILAR VOLUMES
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The functionalized tricyclic framework (XI) of the diterpene forskolin is synthesized by an intramolecular Diels-Alder reaction of the dienyne (VII), which is obtained by stereoselective introduction of the C side chains at C-1 and C-2 of tri-O-acetyl-D-galactal (I) via C-Ferrier and Claisen-Ireland