Synthetic studies on ecteinascidin 743:
โ
Wei Jin; Robert M Williams
๐
Article
๐
2003
๐
Elsevier Science
๐
French
โ 198 KB
The asymmetric synthesis of the modified tyrosine derivative as a basic building block for the ecteinascidin and safracin family of antitumor alkaloids has been achieved in nine steps and 39% overall yield.