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Synthetic routes for the generation of 7,7-dialkyl azepin-2-ones

✍ Scribed by Jeffrey A. Robl; Ellen Sieber-McMaster; Richard Sulsky

Book ID
104255900
Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
235 KB
Volume
37
Category
Article
ISSN
0040-4039

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✦ Synopsis

Three diverse synthetic routes to C-7 dialkylated and spiro-alkylated azepinones are described. Compounds of this type may be used as conformationally restricted dipeptide surrogates. Additionally, the chiral synthesis of novel cyclopropanated lysine derivative 29 is demonstrated.

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