Three diverse synthetic routes to C-7 dialkylated and spiro-alkylated azepinones are described. Compounds of this type may be used as conformationally restricted dipeptide surrogates. Additionally, the chiral synthesis of novel cyclopropanated lysine derivative 29 is demonstrated.
โฆ LIBER โฆ
A program for the FORWARD generation of synthetic routes
โ Scribed by Hendrickson, James B.; Parks, Camden A.
- Book ID
- 127147712
- Publisher
- American Chemical Society
- Year
- 1992
- Tongue
- English
- Weight
- 890 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0095-2338
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