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Tin-Free Radical Cyclizations for the Synthesis of 7-Azaoxindoles, 7-Azaindolines, Tetrahydro[1,8]naphthyridines, and Tetrahydro-5 H -pyrido[2,3- b ]azepin-8-ones

✍ Scribed by Bacqué, Eric; El Qacemi, Myriem; Zard, Samir Z.


Book ID
120178254
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
95 KB
Volume
6
Category
Article
ISSN
1523-7060

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Synthesis of 5-phenyl-5,6,7,8-tetrahydro
✍ Thomas Hussenether; Reinhard Troschütz 📂 Article 📅 2004 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 110 KB

## Abstract A new access to 5‐phenyl‐5,6,7,8‐tetrahydro‐1,6‐naphthyridines **25a‐28a** (n=1) and 5‐phenyl‐6,7,8,9‐tetrahydro‐5__H__‐pyrido[3,2‐__c__]azepines **25b‐28b** (n=2) has been developed by first preparing the functional pyridine moiety followed by intramolecular cyclization forming the par