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Synthetic applications of 2-aryl-4-piperidones. VIII. Synthesis of methyl indolo[2,3-a]quinolizidin-2-acetate

✍ Scribed by Mario Rubiralta; Anna Diez; Cristina Vila; Jean-Luc Bettiol; Yves Troin; Marie-Eve Sinibaldi

Book ID: 104224972
Publisher: Elsevier Science
Year: 1992
Tongue: French
Weight: 238 KB
Volume: 33
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)91905-1

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✦ Synopsis

The synthesis of methyl indolo[2,3-a]quinolizidin-2-acetate (21) from lhydroxyethyl-2-[l -(phenylsulfony/)-3-indolyl]piperidine-4-acetate ( 16) by an intramolecular cyclization induced by KrBuO is described.

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