Synthetic and kinetic aspects of nickel-catalysed amination of allylic alcohol derivatives
✍ Scribed by Hervé Bricout; Jean-François Carpentier; André Mortreux
- Book ID
- 108378833
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 616 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
Experimental evidence shows that the DABCO catalysed rearrangement of allylic esterrproceedsvioatwo~mechanism,ratherthanasinglepsth,ashasbeenpreviously proposed. TheeffectivenesofothercatalystsaswellasE:ZratiosfortheseDABCOcatalysed reactions have also been detedmd.
The reaction of different protected alcohols, amines and amides with lithium and a catalytic amount of naphthalene (4 mol %) in THF at low temperature leads to their deprotection under very mild reaction conditions, the process being in many cases chemoselective.