Synthesis of γ-[15N]-L-glutamyl derivatives of 5,10-dideazatetrahydrofolate
✍ Scribed by Ronald A. Forsch; Andre Rosowsky
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- French
- Weight
- 416 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0022-2135
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📜 SIMILAR VOLUMES
## Abstract Adenylyl imidodiphosphate, specifically ^15^N labelled in the β,γ‐bridging nitrogen position, was synthesized in 5% overall yield from ^15^NH~3~.
## Abstract [Cys‐^14^CO]‐glutathione or N‐[N‐L‐γ‐glutamyl‐L‐cysteinyl‐^14^CO] glycine was prepared by chemical synthesis, with the L,L‐natural configuration and a radiochemical yield of 1% based on sodium [^14^C] cyanide. This labelled compound was used to obtain [Cys‐^14^CO] with a yield of 15%. [
## Synopsis C Z ~H : ~~N ~O ~, orthorhombic, B212121; a = 39.432 (lo), b = 14.061 ( 5 ) , c = 4.850 (2) A, M = 494 a.m.u., Z = 4, Dm = 1.22 g cm-:', Dr = 1.22 g cm-3, R = 0.13 for 1205 observed reflections alter refinement with isotropic thermal factors. The urethane and amide bonds are in the tra