2004 Carbohydrates Carbohydrates U 0500 Synthesis of β-D-Galp-(1→4)-β-D-GlcpNAc-(1→2)-α-D-Manp-(1→O)(CH 2 ) 7 CH 3 Mimics to Explore the Substrate Specificity of Sialyltransferases and trans-Sialidases. -(JOOSTEN,
Synthesis of β-d-GlcpNAc-(1 → 2)-5a-carba-α-d-Manp-(1 → 6)-β-d-Glcp-O(CH2)7CH3: a reactive acceptor analog for N-acetylglucosaminyltransferase-V
✍ Scribed by Seiichiro Ogawa; Takashi Furuya; Hidetoshi Tsunoda; Ole Hindsgaul; Katja Stangier; Monica M. Palcic
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 483 KB
- Volume
- 271
- Category
- Article
- ISSN
- 0008-6215
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## Abstract Three trisaccharide derivatives of the type β‐D‐Hex__p__‐(1 → 4)‐β‐D‐Glc__p__NAc(1 → 2)‐α‐D‐Man__p__‐(1 → O)(CH~2~)~7~CH~3~ have been synthesized, with Hex being either glucose (15), 4‐deoxy‐4‐fluorogalactose (20), or 4‐deoxygalactose (27). These trisaccharides have been designed for th
Synthesis of Protected Hexp-(1 → 4)-β-D-GlcpNAc-(1 → 2)-α-D-Manp-(1 → O)(CH2)7CH3 Sequences (Hex: β-D-Glc, 4-deoxy-4fluoro-β-D-Gal, or 4-deoxy-β-D-Gal) Using a Glc-GlcNPhth Donor, Eventually Fluorinated or Deoxygenated at the Oligosaccharide Level. -The title trisaccharide derivatives are prepared