Synthesis of α-Glucuronic Acid and Amide Derivatives in the Presence of a Participating 2-Acyl Protecting Group
✍ Scribed by Tosin, Manuela; Murphy, Paul V.
- Book ID
- 118160821
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 196 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1523-7060
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A novel and general route for the solid phase synthesis of N-substituted α-amino acids has been developed. This synthesis employs Fukuyama's 2-nitrobenzenesulfonamide protecting group for preparation of secondary amines. The versatility of this methodology is demonstrated by the facile synthesis of