Synthesis of well-defined poly[(2-β-D-glucopyranosyloxy)ethyl acrylate] by atom transfer radical polymerization

✍ Scribed by Liang, Yu-Zeng; Li, Zi-Chen; Chen, Guang-Qiang; Li, Fu-Mian

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 78 KB
• Volume: 48
• Category: Article
• ISSN: 0959-8103
• DOI: 10.1002/(sici)1097-0126(199909)48:9<739::aid-pi283>3.0.co;2-6

✦ Synopsis

The `living' radical polymerization of 2-(2',3',4',6'-tetra-O-acetyl-b-D-glucopyranosyloxy)ethyl acrylate (AcGEA) by atom transfer radical polymerization (ATRP) is reported. It has been found that the polymerization kinetics are ®rst-order, the molecular weights increase linearly with conversion, and the molecular weight distribution remains narrow when the polymerization conversion is below 70%. Well-de®ned P(AcGEA) was obtained, and the O-protecting acetyl groups of P(AcGEA) were quantitatively removed by reacting with dilute CH 3 ONa solution in CHCl 3 /CH 3 OH to afford well-de®ned poly[(2-b-D-glucopyranosyloxy)ethyl acrylate] (PGEA).