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Synthesis of (+)-vernolepin related compounds from germacranolides

✍ Scribed by Alejandro F. Barrero; J.Enrique Oltra; Armando Barragán

Book ID
103399740
Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
233 KB
Volume
36
Category
Article
ISSN
0040-4039

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Synthesis of elemane bis-lactones struct
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✍ Gonzalo Blay; Luz Cardona; Begoña García; Luisa Lahoz; JoséR Pedro 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 191 KB

The chemical transformation of santonin into an elemane bis-lactone structurally related to the antitumour compound vemolepin is reported. The transformation of ring A of santonin into a hemiacetal ~-lactone was achieved in eleven steps. The spectroscopic characteristics of the synthetic product obt