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Stereoselective synthesis of racemic elemanolide dilactones related to vernolepin

✍ Scribed by Marshall, James A.; Flynn, Gary A.


Book ID
126446969
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
1021 KB
Volume
44
Category
Article
ISSN
0022-3263

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Synthesis of elemane bis-lactones struct
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The chemical transformation of santonin into an elemane bis-lactone structurally related to the antitumour compound vemolepin is reported. The transformation of ring A of santonin into a hemiacetal ~-lactone was achieved in eleven steps. The spectroscopic characteristics of the synthetic product obt