Synthesis of Twisted Intercalating Nucleic Acids Possessing Acridine Derivatives. Thermal Stability Studies
✍ Scribed by Géci, Imrich; Filichev, Vyacheslav V.; Pedersen, Erik B.
- Book ID
- 121306266
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 304 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1043-1802
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract __Intercalating nucleic acids (INA®s) with insertions of (__R__)‐1‐__O__‐(1‐pyrenylmethyl)glycerol were hybridized with locked nucleic acids (LNAs). INA/LNA duplexes were found to be less stable than the corresponding DNA/LNA duplexes when the INA monomer was inserted as a bulge close t
## Abstract A postsynthetic, on‐column Sonogashira reaction was applied on DNA molecules modified by 2‐ or 4‐iodophenylmethylglycerol in the middle of the sequence, to give the corresponding __ortho__‐ and __para__‐twisted intercalating nucleic acids (TINA) with 1‐, 2‐, and 4‐ethynylpyrene residues