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Synthesis of Tubuphenylalanines via Ireland–Claisen Rearrangement

✍ Scribed by Becker, Dominic; Kazmaier, Uli


Book ID
118734408
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
312 KB
Volume
78
Category
Article
ISSN
0022-3263

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✍ Hideo Tokuhisa; Yoshinobu Nagawa; Hirotaka Uzawa; Kazuhisa Hiratani 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 245 KB

A synthetic route for crownophanes containing a chiral binaphthyl unit using tandem Claisen rearrangement is described to demonstrate the versatility of this approach. Molecular recognition by the resulting crownophane for butylurea is also investigated.