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Synthesis of tritium labeled zomepirac

✍ Scribed by David C. Hoerr; Ann T. Scharf; John R. Carson; Larry E. Weaner

Publisher: John Wiley and Sons
Year: 1983
Tongue: French
Weight: 378 KB
Volume: 20
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580201210

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✦ Synopsis

Abstract

Tritium labeled zomepirac with a specific activity of 85 Ci/mol was prepared by selective alkylation of the penultimate desmethyl precursor using methyl iodide‐^3^H~3~. The alkylation reaction was explored using various bases and solvent media.

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