Sir, Latli and coworkers recently described a synthesis of tritium-labelled bilirubin by the reduction of biliverdin with sodium borotritiide. 1 They failed to note that an essentially identical, but faster and higher-yield, procedure was published in this journal by Hutchinson et al. in 1981 2 and
Synthesis of tritium-labeled bilirubin
β Scribed by Bachir Latli; Matt Hrapchak; Dhileepkumar Krishnamurthy; Chris H. Senanayake
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- French
- Weight
- 153 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0022-2135
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β¦ Synopsis
Abstract
Tritiumβlabeled bilirubin with specific activities ranging from 6.8 to 8.8βCi/mmol was prepared in a single step by reducing biliverdin dihydrochloride with sodium borotritide in ethanol. Copyright Β© 2008 John Wiley & Sons, Ltd.
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Sir, it has been brought to our attention that in our manuscript published in JLCR 1 we neglected to cite an earlier procedure by Hutchinson et al. 2 We regret this oversight, although our paper described improvements over previous procedures. For example, our manuscript describes for the first time
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