𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of [trifluoromethyl-[14C6]-phenyl]-SR 57746A

✍ Scribed by N. Robic; J-P. Noël

Publisher
John Wiley and Sons
Year
1999
Tongue
French
Weight
356 KB
Volume
42
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of 14C-labelled 1-(3,5-bis-tri
Synthesis of 14C-labelled 1-(3,5-bis-trifluoromethyl)-phenyl-4-methyl thiosemicarbazide, C 2696-GO
✍ R. K. Maller; K. Nagarajan; H. Zoebeli 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 French ⚖ 368 KB

For pharmacokinetic and metabolism s t u d i e s i n e x p e r i m e n t a l animals C 2 6 9 6 4 0 was l a b e l l e d i n i t i a l l y w i t h 14C on t h e t h i o c a r b o n y l carbon of t h e t h i o s e m i c a r b a z i d e moiety o f t h e molecule, having a s p e c i f i c a c t i v i t y

Synthesis of 3-phenyl-5-(trifluoromethyl
Synthesis of 3-phenyl-5-(trifluoromethyl)isoxazole and 5-phenyl-3-(trifluoromethyl)isoxazole
✍ James W. Pavlik; Jennifer A. Lowell; Vuthichai Ervithayasuporn 📂 Article 📅 2005 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 65 KB

Reaction of 4,4,4-trifluoro-1-phenyl-1,3-butanedione with hydroxylamine led to the formation of 5hydroxy-3-phenyl-5-(trifluoromethyl)-4,5-dihydroisoxazole which was dehydrated to 3-phenyl-5-(trifluoromethyl)isoxazole. This isomer can also be synthesized by reaction of 4-chloro-4-phenyl-1,1,1-trifluo

Synthesis of [14C]-labelled tolrestat(N-
Synthesis of [14C]-labelled tolrestat(N-[[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]-[14C]thioxomethyl]-N-methylglycine; AY-27, 773)
✍ D. R. Hicks 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 French ⚖ 265 KB

## Abstract [^14^C]‐Tolrestat(N‐[[5‐(trifluoromethyl)‐6‐methoxy‐1‐naphthalenyl]‐[^14^C]‐thioxomethyl]‐N‐methylglycine; [14C]AY‐27, 773), a new aldose reductase inhibitor, was prepared by incorporating [14C]carbon dioxide. The intermediate, 6‐methoxy‐5‐trifluoromethyl‐[1–14C]‐naphthoic acid, prepare

Synthesis of 6-substituted benzo[a]pyren
Synthesis of 6-substituted benzo[a]pyrene-α-14C derivatives
✍ James L. Hicks; J. Richard Heys 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 332 KB

## Abstract 6‐Lithiobenzo[__a__]pyrene was carbonated to produce benzo[__a__]pyrene‐6‐carboxylic‐^14^C acid, which was in turn used in the preparation of several derivatives. Methylation to the ester was followed by LiAlH~4~ reduction to 6‐hydroxymethyl‐^14^C‐benzo[__a__]pyrene. An efficient oxidat