Synthesis of thiazoles from the reaction of phenyliodonium ylids of cyclic β-dicarbonyl compounds with thioureas
✍ Scribed by Heleni Kamproudi; Spyros Spyroudis; Petroula Tarantili
- Book ID
- 112131505
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1996
- Tongue
- English
- Weight
- 229 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0022-152X
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📜 SIMILAR VOLUMES
## Abstract An efficient and mild reaction for introducing an allylic moiety and an alkylthio‐ or alkylseleno‐group onto the α‐carbon of β‐dicarbonyl compounds in one step by tandem transylidation and [2,3]‐sigmatropic rearrangement is described.
Tetranethoxyethylene (TIIE) is a highly nucleophilic alkene that reacts with methanol, malononitrile or benmic acid to give the addition products, pentaoethoxyethane, 1,2,2~trimethoxyethyltdenemalononitrile and 1,1,2,2-tetramethoxyethyl benxoate respectively'. Roreover, the last product decomposes t