Synthesis of the upper fragment of tetronolide
โ Scribed by Takeda, Kei; Kato, Hideki; Sasahara, Hiroya; Yoshii, Eiichi
- Book ID
- 111966521
- Publisher
- The Royal Society of Chemistry
- Year
- 1986
- Tongue
- English
- Weight
- 187 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0022-4936
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๐ SIMILAR VOLUMES
## The first total synthesis of tetronolide (1) has been achieved via coupling of spirotetronate 3 with octahydronaphthalene aldehyde I7 and subsequent macrocyclization of wsulfone-a-nldehydeone-a-aldehyde 2, leading to confirmation of the absolute configuration of 1. Tetronolide (1) is the aglyco
An efficfent enanboseieciwe route to the actahydronaphlhabne uaf preseni II) tetronollde (I), the stereochem~calty complex aglycone common to the telrocarcms, a novel group of anlilumor substances, IS described The sequence employs the mtramolecular D/e/s-Aider reaction to control the relatrve stere