Synthesis of the preparations pyrroxan and butyroxan labeled with the radioactive isotope14C
โ Scribed by B. Z. Askinazi; S. M. Chizhik; N. Ya. Kozarinskaya
- Book ID
- 112407636
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 364 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0091-150X
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๐ SIMILAR VOLUMES
## Abstract A oneโpot reaction scheme leading to ^14^Cโlabeled pargyline (NโmethylโNโ propargylbenzylamine) where in the radioactive label from [^14^C]โformaldehyde is synthetically incorporated into the methylene group of the propargyl side chain is described. Thus, [^14^C]โformaldehyde (aqueous s
## Abstract Dimethoxymethyl phenobarbital (DMMP), labeled with ^14^C on the ring and side chains was prepared for drug metabolism studies. The synthesis of DMMPโethylโ1โ^14^C (4a) in four steps provided a 43% yield from ethylโ1โ^14^C iodide. The yields of DMMPโ2โ^14^C (4b) and DMMPโdimethyleneโ^14^