Synthesis of the enantiopure C15–C26 segment of phorboxazole A and B
✍ Scribed by Peter Wolbers; Andrea M. Misske; H. Martin R.%Hoffinann
- Book ID
- 104261586
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 209 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Two approaches towards an enantiopure C15-C26 segment of the phorboxazoles starting from the corresponding C20-C26 aldehyde are presented. A variety of functionalized oxazoles have been synthesized via the rhodium(lI) acetate catalyzed cycloaddition of dimethyl diazomalonate to substituted nitriles.
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