𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of the chiral acyclonucleoside antiherpetic agent (S)-9-(2,3-dihydroxy-1-propoxymethyl)guanine

✍ Scribed by Malcolm MacCoss; Anna Chen; Richard L. Tolman

Book ID
108382542
Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
203 KB
Volume
26
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Efficacy of (S)-1-(3-hydroxy-2-phosphony
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for the treatment of murine cytomegalovirus infection in severe combined immunodeficiency mice
✍ Johan Neyts; Jan Balzarini; Lieve Naesens; Erik de Clercq πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 540 KB

## Abstract Mice with severe combined immunodeficiency (SCID) inoculated intraperitoneally with murine cytornegalovirus (MCMV) develop a wasting syndrome at 3–4 days and die at 6–9 days after the infection. 9‐(1,3‐Dihydroxy‐2‐propoxyrnethyl)guanine (DHPG, ganciclovir) and (__S__)‐1‐(3‐hydroxy‐2‐pho