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Synthesis of the Bicyclo[7.3.0]dodecadiyne Core of the Maduropeptin Chromophore

โœ Scribed by Kentaro Iso; Masayuki Inoue; Nobuki Kato; Masahiro Hirama


Book ID
112005385
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
251 KB
Volume
3
Category
Article
ISSN
1861-4728

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Synthetic studies on maduropeptin chromo
โœ K.C. Nicolaou; Kazunori Koide ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 220 KB

The aryl ether system of the maduropeptin chromophore artifact I was constructed via an aldol type condensation (7+6, Schemes 1 and 2, 7+19, Scheme 4), but attempted synthesis and ring closure of aldehyde 25 (Scheme 4) to afford the enediyne core of 1 failed.