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Synthesis of the Bicyclic [7.3.0] Enediyne System of the Maduropeptin Chromophore: Remarkable Atropisomerism of Ansamacrolactam and Isomerization of the C4—C13 Double Bond.

✍ Scribed by Nobuki Kato; Satoshi Shimamura; Yoko Kikai; Masahiro Hirama


Publisher
John Wiley and Sons
Year
2005
Weight
12 KB
Volume
36
Category
Article
ISSN
0931-7597

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📜 SIMILAR VOLUMES


Synthetic studies on maduropeptin chromo
✍ K.C. Nicolaou; Kazunori Koide 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 220 KB

The aryl ether system of the maduropeptin chromophore artifact I was constructed via an aldol type condensation (7+6, Schemes 1 and 2, 7+19, Scheme 4), but attempted synthesis and ring closure of aldehyde 25 (Scheme 4) to afford the enediyne core of 1 failed.

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