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Synthesis of tertiary α-amino phosphonate by one-pot three-component coupling mediated by LPDE

✍ Scribed by Najmedin Azizi; Mohammad R. Saidi

Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
111 KB
Volume
59
Category
Article
ISSN
0040-4020

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✦ Synopsis

A very mild, efficient and simple method for the synthesis of tertiary a-amino phosphonates is reported by reaction of an aldehyde, a secondary amine and trialkylphosphite in ethereal solution of lithium perchlorate, LPDE, at ambient temperature with high yields.

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