✦ LIBER ✦

Synthesis of sulfamide linked dinucleotide analogues

✍ Scribed by Jason Micklefield; Kevin J. Fettes

Publisher: Elsevier Science
Year: 1997
Tongue: French
Weight: 220 KB
Volume: 38
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(97)01179-9

No coin nor oath required. For personal study only.

✦ Synopsis

Novel sulfamide [-NHSO2NH-] linked dinucleotide analogues d(TnsnT) and d(TnsnA) have been synthesised from 3"--and 5"-amino nucleosides. Treatment of these amino nucleosides with catechol sulfate results in the formation of 2-hydroxyphenyl sulfamate esters which couple smoothly in good yields with either 5"--or 3"-amines of similar nucleosides. NMR studies showed that the 3"sulfamide group results in a preferential C3"--endo (Northern) sugar conformation.

📜 SIMILAR VOLUMES

Synthesis of novel carbazoyl linked pyri

Synthesis of novel carbazoyl linked pyrimidine-pyrimidine and pyrimidine-purine dinucleotide analogues

✍ Julia Magdalena; Susana Fernández; Miguel Ferrero; Vicente Gotor 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 224 KB

The synthesis of two backbone modified dinucleotide analogues is described in which the natural phosphodiester linkage is replaced by a 3'-5" c~xbazoyl linkage. In both cases the bridge was formed through a coupling reaction between an appropriate 3'-carbazoyl nucleoside analogue and an aldehyde nuc

ChemInform Abstract: Synthesis of Novel

ChemInform Abstract: Synthesis of Novel Carbazoyl-Linked Pyrimidine—Pyrimidine and Pyrimidine—Purine Dinucleotide Analogues.

✍ Julia Magdalena; Susana Fernandez; Miguel Ferrero; Vicente Gotor 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 27 KB 👁 1 views

ChemInform Abstract: Synthesis of Analog

ChemInform Abstract: Synthesis of Analogues of Nucleotides with All-Carbon Backbones: Synthesis of N-Protected C-Linked Dinucleotides

✍ K. BUTTERFIELD; E. J. THOMAS 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views

Synthesis of a thymidine dinucleotide an

Synthesis of a thymidine dinucleotide analogue containing an internucleotide silyl linkage

✍ K.K. Ogilvie; J.F. Cormier 📂 Article 📅 1985 🏛 Elsevier Science 🌐 French ⚖ 241 KB

Preparation of formacetal-linked purine-

Preparation of formacetal-linked purine-purine dinucleotide analogs

✍ Gong-Xin He; Norbert Bischofberger 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 213 KB

Protected formacetal-linked purine-purine dinucleotide analogs, including dG-f-dG, dG-f-dA, dA-f-dG, and dA-f-dA, were synthesized for the first time in 40 -60% yields by condensation of the 5'-OH group with the 3'-OCH2SCH3 group of the two corresponding deoxynucleoside units using N-iodosuccinimide

ChemInform Abstract: Synthesis of Novel

ChemInform Abstract: Synthesis of Novel Nα,Nε-Lysine Linked Dinucleotides

✍ Yu-Fen Zhao; Bo Han; Gang Zhao; Hua Fu 📂 Article 📅 2000 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v