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Synthesis of substrate analogues for trypanothione reductase

โœ Scribed by EL-WAER, ABDUSSALAM F. ;BENSON, TIMOTHY ;DOUGLAS, KENNETH T.

Book ID
115099437
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
484 KB
Volume
41
Category
Article
ISSN
0367-8377

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Convenient synthesis of disulfide substr
Convenient synthesis of disulfide substrates for trypanothione reductase using polymer-supported reagents
โœ Kelly Chibale; Alex Chipeleme; Stuart Warren ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 59 KB

Operationally simplified and high yielding methods for the preparation of N,N%-bis(benzyloxycarbonyl)-1-L-cysteinylglycyl-3-dimethylaminopropylamide disulfide, an alternative substrate for trypanothione reductase, and a structural analogue, using polymer-supported reagents are described.