Synthesis of Spirocyclic Indolines by Interruption of the Bischler–Napieralski Reaction
✍ Scribed by Medley, Jonathan William; Movassaghi, Mohammad
- Book ID
- 120512599
- Publisher
- American Chemical Society
- Year
- 2013
- Tongue
- English
- Weight
- 594 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1523-7060
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Table 1. Side-chain alkylation of toluene with ethylene. Cr-Ni-Mo steel autoclave (314 cm'), 20 g (217 mmol) toluene, 7 g (250 mmol) ethylene. 380 C. 55 atm, 2 h. C , H,CH,Br Toluene Yield [mol-";,I all straight [ w1:y J conversion n-propyi-,~-pentyl-chain alkyl-C%1 benzene benzene benzenes
Ethylene ketals of the type (I) cyclise in presence of phosphorus pentoxide in pyrid& to give the ketal (II) which on hydrolysis yields l-phenyl-6:7-dimethoxy4oxo-3:4-dihydroisquinob (III). 1-(4-oxo-cyclohexyl)-6:7-dimethoxy-3:4-dihydroisoquinoline (Vlll) and 2-oxo-3-methyl-g:1& dimethoxy-I 2:3:4:6: