## Abstract Local anesthetics procaine and tetracaine have been specificallyโdeuterated in two and three positions, respectively, for use in deuterium nuclear magnetic resonance experiments. The experimental procedure is either new or an adaptation of early synthetic methods.
Synthesis of specifically deuterated saturated and unsaturated phosphatidylserines
โ Scribed by Jeffery Browning; Joachim Seelig
- Book ID
- 107736939
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 789 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0009-3084
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## Abstract Site specific deuterated primaquines were prepared. The attempts to prepare these by deuterolysis of bromoprimaquines were unsuccessful because the required bromoprimaquines could not be produced satisfactorily by alkylation of the various bromoโ6โ methoxyโ8โaminoquinolines. Instead pri
## Abstract Two site specifically deuterated primaquines were prepared. 4โฒ,4โฒโDideutero primaquine **3** was obtained from the corresponding dideutero alcohol which was prepared by the low temperature reduction of the ester compound **4** with lithium aluminium deuteride. 1โฒโDeutero primaquine r wa