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Synthesis of some pyrazolyl benzenesulfonamide derivatives as dual anti-inflammatory antimicrobial agents

✍ Scribed by Bekhit, Adnan A.; Ashour, Hayam M. A.; Bekhit, Alaa El-Din A.; Abdel-Rahman, Hamdy M.; Bekhit, Salma A.

Book ID
120248153
Publisher
Informa plc
Year
2009
Tongue
English
Weight
335 KB
Volume
24
Category
Article
ISSN
1475-6366

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## Abstract Four series of 1 __H__‐pyrazole derivatives have been synthesized. The first series was synthesized starting with the reaction of 3‐(5‐bromo‐2‐thienyl)‐1‐phenyl‐1 __H__‐pyrazole‐4‐carboxaldehyde **1** with L‐serine, L‐cysteine, or L‐penicillamine, followed by __N__‐protection using (Boc