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Design and synthesis of some substituted 1H-pyrazolyl-thiazolo[4,5-d]pyrimidines as anti-inflammatory–antimicrobial Agents

✍ Scribed by Adnan A Bekhit; Hesham T.Y Fahmy; Sherif A.F Rostom; Azza M Baraka


Book ID
108422026
Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
253 KB
Volume
38
Category
Article
ISSN
0223-5234

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Design and Synthesis of Some Substituted
✍ Adnan A. Bekhit; Hesham T. Y. Fahmy 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 181 KB 👁 1 views

## Abstract Four series of 1 __H__‐pyrazole derivatives have been synthesized. The first series was synthesized starting with the reaction of 3‐(5‐bromo‐2‐thienyl)‐1‐phenyl‐1 __H__‐pyrazole‐4‐carboxaldehyde **1** with L‐serine, L‐cysteine, or L‐penicillamine, followed by __N__‐protection using (Boc