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Synthesis of new oxadiazole derivatives as anti-inflammatory, analgesic, and antimicrobial agents

✍ Scribed by Ramaprasad, G. C.; Kalluraya, Balakrishna; Sunil Kumar, B.; Mallya, Sahana

Book ID
120576846
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
323 KB
Volume
22
Category
Article
ISSN
1054-2523

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## Abstract A series of new 3‐(substituted) 3‐hydroxy‐propanoic acid ethyl esters **1a–c**, hydrazides **2a–c**, thiosemicarbazides **3a–f**, and semicarbazides **3g**, **3h** has been synthesized. Cyclization of compounds **3a–d** in basic medium yielded 1,2,4‐triazole‐5‐thiones **4a–d**. On the o