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Synthesis of Some New Quinoxalines and 1,2,4-Triazolo[4,3-a]quinoxalines for Evaluation of in vitro Antitumor and Antimicrobial Activities.

✍ Scribed by Soad A. M. El-Hawash; Nargues S. Habib; Mervat A. Kassem


Publisher
John Wiley and Sons
Year
2007
Weight
26 KB
Volume
38
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.


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## Abstract Some 1,2,4‐triazolo[4,3‐__a__]quinoxalines 1–10, and 1,2,4‐triazino[4,3‐__a__]quinoxalines 11–12 were prepared and biologically evaluated for their binding at the benzodiazepine receptor (BZR) in rat cortical membranes. The BZR affinity of 1–10 demonstrates that the presence of a proton