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ChemInform Abstract: Quinoxaline Derivatives. Part 2. Synthesis and Antimicrobial Testing of 1,2,4-Triazolo[4,3-a]quinoxalines, 1,2,4-Triazino[4,3-a]quinoxalines and 2-Pyrazolylquinoxalines.

✍ Scribed by S. A. El-Hawash; N. S. Habib; N. H. Fanaki


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
31
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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Tricyclic Heteroaromatic Systems. 1,2,4-
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## Abstract Some 1,2,4‐triazolo[4,3‐__a__]quinoxalines 1–10, and 1,2,4‐triazino[4,3‐__a__]quinoxalines 11–12 were prepared and biologically evaluated for their binding at the benzodiazepine receptor (BZR) in rat cortical membranes. The BZR affinity of 1–10 demonstrates that the presence of a proton