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Synthesis of Some 9-(Aminoalkyl)-6,7-dihydropyrimido[2,1-f]-purine-2,4,8-(1H,3H,9H)triones Synthese einiger 9-(Aminoalkyl)-6,7-dihydropyrimido[2,1-f]purin-2,4,8-(1H,3H,9H)trione

✍ Scribed by Maciej Pawlowski; Armin Buschauer; Walter Schunack


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
180 KB
Volume
322
Category
Article
ISSN
0365-6233

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✍ Yandong Zhang; Chao Yao; Richard A. Houghten; Yongping Yu 📂 Article 📅 2007 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 117 KB

## Abstract An approach for the solid‐phase synthesis of 4,8‐disubstituted‐8,9‐dihydropyrazino[2,3‐__g__]quinazolin‐7(6__H__)‐ones from 4‐chloro‐7‐fluoro‐6‐nitroquinazoline scaffold is described. A chemoselective reaction of resin‐bound arylamines (**3**) with 4‐chloro‐7‐fluoro‐6‐nitroquinazoline (