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Synthesis of some 14C-labelled aziridine compounds, psychotropic agents

✍ Scribed by H. Minato; T. Nagasaki; Y. Katsuyama; T. Yokoshima; K. Suga; T. Ueda

Publisher
John Wiley and Sons
Year
1977
Tongue
French
Weight
357 KB
Volume
13
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

1‐Methyl‐2‐(2‐naphthyl)aziridine (1) and 1‐methyl–2‐(1,2,3,4‐tetrahydro‐2‐naphthyl)aziridine (II), psychotropic agents, were labelled by incorporating carbon‐14 into the carbon of the aziridine ring. Labelled products I and II were obtained in 32.4% and 14.4% radiochemical yield based on 2‐acetyl‐carbonyl‐^14^C‐naphthalene (III), respectively.

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